QbD and PAT: From Science to Compliance
Boards of health like the Food and Drug Administration and European Medicines Agency and ICH guidelines Q8, Q9 and Q10, provide a framework for Quality by Design (QbD) that fully integrates drug...
View ArticleDrug-drug interactions: tools for drug transporter protein studies
Drug transporters are membrane proteins involved in the uptake or efflux of drugs by several tissues such as the intestine, liver, kidney and brain. They can have a significant impact on the...
View ArticleReal-time environmental monitoring: PAT solutions using rapid microbiological...
In these economic times the pharmaceutical industry has expressed a renewed interest to explore ways in which to enhance the efficiency and agility of existing and future manufacturing processes. This...
View ArticleDrug Discovery 2009 – In association with SBS and BPS
Going from strength to strength ELRIG are pleased to announce the 3rd Drug Discovery Symposium. This year ELRIG will be joined by the BPS (British Pharmacological Society) for the event. The post Drug...
View ArticleCellular Imaging & Analysis Business Unit
Mark Collins from Thermo Fisher Scientific, who provide analytical instruments, laboratory equipment, software, services, consumables and reagents, talks to us about current developments and future...
View ArticleHigh throughput and high content screening microscopy: A microscopy based...
The understanding of properties of any biological system requires a detailed and quantitative analysis of its parts and their interactions. As different processes within a system occur at defined space...
View ArticleNew DNA sequencing technologies: applications, promises and challenges for...
We are currently on the cusp of a technology-driven revolution in the field of genomics. The rapid evolution of DNA sequencing technology is already providing researchers with the ability to generate...
View ArticleArticle 4: Optimisation of the PCR step of a qPCR assay
The deceptive simplicity of a typical qPCR assay is an important reason for the exponential growth in the adoption of qPCR-related technologies for both research and diagnostic applications. The only...
View ArticleRNAi applications in biology and medicine
The field of oligonucleotide-based therapy experienced a revival with the discovery of RNA interference (RNAi) in 19981. RNAi is a conserved endogenous mechanism, which is triggered by double-stranded...
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